FOP - Lines of Research

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Piracicaba School of Dentistry

Research lines

PREVENTION IN DENTISTRY. It aims to study the effectiveness of the main methods of preventing the main diseases in dentistry, as well as associated factors, in order to control the disease based on a philosophy of health promotion (Approved by the Department/Scientific Council in 2006). Line linked to the SOCIAL DENTISTRY DEPARTMENT.

ISOLATION, IDENTIFICATION AND CLONALITY OF PERIODONTOPATHGENS. Detection of periodontopathogens and periodontal pockets using the PCR technique. Correlation between the presence or absence of these microorganisms and clinical parameters. (Approved by the Department/Scientific Council in 1992). Line connected to the ORAL DIAGNOSTIC DEPARTMENT.

MATERIALS FOR BASE, LINERS, FASTENERS AND MOLDING. Study of the influence of base materials, linings, fasteners and molding involving aspects of mechanical resistance, resistance to removal by traction and shear, as well as microleakage, adaptation strength and dimensional stability. Germicidal properties and biological compatibility with oral tissues. Its characteristics and uses. (Approved by the Department/Scientific Council in 2002). Line connected to the DEPARTMENT OF RESTORATIVE DENTISTRY.

METALS, METAL ALLOYS, CASTING AND WELDING PROCESS. Study of the characteristics of dental metals and alloys. Analysis and behavior of parts cast by different processes in foundry machines. Analysis of the welded structure in metallic alloys used in fixed and removable partial dentures. (Approved by the Department/Scientific Council in 2002). Line connected to the DEPARTMENT OF RESTORATIVE DENTISTRY.

ACRYLIC RESINS, COMPOSITES AND ADHESIVES FOR DENTAL USE. Resins, composites and adhesives play an important role in the development of restorative dentistry. Thus, the objective of this line is to study the composition, structure and chemical and physical properties. Types of polymerization. Handling and use techniques. Dimensional change. (Approved by the Department/Scientific Council in 2002). Line connected to the DEPARTMENT OF RESTORATIVE DENTISTRY.

APOPTOSIS AND FACTORS RELATED TO CHANGES IN BONE TISSUE METABOLISM. Investigates the changes involved in cell-extracellular matrix interactions in bone tissue. Observations resulting from basic research are correlated to clinical issues involving periodontal disease. (Approved by the Department/Scientific Council in 2000). Line linked to the DEPARTMENT OF MORPHOLOGY.

STUDY OF CRANIO-FACIAL GROWTH, BONE MATURATION AND DEVELOPMENT OF OCCLUSION. STUDY OF CRANIAL-FACIAL GROWTH, BONE MATURATION AND DEVELOPMENT OF OCCLUSION (Approved by the Department/Scientific Council in 2006). Line connected to the ORAL DIAGNOSTIC DEPARTMENT.

CEPHALOMETRY. CEPHALOMETRY (Approved by the Department/Scientific Council in 2006). Line connected to the ORAL DIAGNOSTIC DEPARTMENT.

Cavities diagnosis. This line of research seeks information on the treatment philosophy, histopathology, clinical characteristics and treatment decision related to the diagnosis of dental caries (Approved by the Department/Scientific Council in 2006). Line linked to the SOCIAL DENTISTRY DEPARTMENT.

Health education. This line of research seeks to study the effectiveness of health education procedures and audio-visual resources commonly used to teach hygiene techniques (Approved by the Department/Scientific Council in 2006) . Line linked to the SOCIAL DENTISTRY DEPARTMENT.

Epidemiology of the main oral diseases. This line of research seeks to study the distribution and occurrence of the main oral diseases, as well as the causative factors. Furthermore, it seeks to investigate factors linked to sample design, clinical epidemiology and epidemiological surveillance (Approved by the Department/Scientific Council in 2006). Line linked to the SOCIAL DENTISTRY DEPARTMENT.

Dental fluorosis and fluorosis biochemistry. Searches for information on the epidemiology, factors that increase the risk, histopathology and clinical characteristics of dental fluorosis, as well as the biochemistry of the main changes in the oral environment (Approved by the Department/ Scientific Council in 2006). Line linked to the SOCIAL DENTISTRY DEPARTMENT.

Health Management in Dentistry. This line of research seeks to describe factors related to service administration, labor market, health surveillance, human resources, management of special patients, planning, health policies and models assistance (Approved by the Department/Scientific Council in 2006). Line linked to the SOCIAL DENTISTRY DEPARTMENT.

HEALTH EDUCATION AND PSYCHOLOGY. The contribution of Psychology in Health Education Programs has helped the implementation of intra-mural and extra-mural programs that aim to raise awareness among the population and produce changes in behavior. This line of research also seeks to study the effectiveness of psychological preparation and guidance in Oral Health Education. (Approved by the Department/Scientific Council in 1991). Line linked to the SOCIAL DENTISTRY DEPARTMENT.

DENTAL ETHICS AND LEGISLATION. Research in this line aims to study the ethical and legal aspects of the dental profession, as well as the hermeneutics of current ethical and legal dental legislation. (Approved by the Department/Scientific Council in 1990). Line linked to the SOCIAL DENTISTRY DEPARTMENT.

ELECTROMYOGRAPHY. Perform electromyographic analysis on muscles related to chewing, swallowing and posture of individuals. Myofacial pain. Vibration. Articulate. (Approved by the Department/Scientific Council in 1993). Line linked to the DEPARTMENT OF MORPHOLOGY.

DENTAL CARE FOR SPECIAL PATIENTS. Dental care for special patients (babies, mentally, hearing and visually impaired; fearful, etc.) constitutes a growing demand for dentistry today. It involves developing and applying clinical, behavioral and educational strategies that enable the provision of this service and the implementation of training programs. This line of research seeks to study the characteristics of care for special patients, integrating the contributions of Psychology and Dentistry. (Approved by the Department/Scientific Council in 1991). Line linked to the SOCIAL DENTISTRY DEPARTMENT.

THE DENTIST SURGEON - PATIENT RELATIONSHIP. The study of the Surgeon-Dentist - patient relationship involves the identification of processes or interactive variables that influence the performance of treatment and its results. Among these variables are *Patient adherence* to clinical interventions and dentist recommendations, the patterns of anxiety and fear that appear in the dental situation and the manifestations of stress (from the professional or the patient) that eventually occur. This line of research seeks an empirical and theoretical elucidation of the processes mentioned above. (Approved by the Department/Scientific Council in 1991). Line linked to the SOCIAL DENTISTRY DEPARTMENT.

COMMUNITY DENTAL CARE: INTEGRATION BETWEEN SERVICE AND RESEARCH. Through a university extension service implemented at FOP-UNICAMP, we seek to identify and develop research projects relevant to the service and integrated with scientific research related to the clinical and behavioral aspects of oral health. Included here are studies related to *CONCEPTION OF ORAL HEALTH*, *GUIDANCE PROGRAMS*, *IMPLEMENTATION OF SERVICES IN THE COMMUNITY*, etc. (Approved by the Department/Scientific Council in 1991). Line linked to the SOCIAL DENTISTRY DEPARTMENT.

FORENSIC TOXICOLOGY. The work in this line of research covers the study of quantitative and qualitative analysis of toxic and poisonous substances and their importance in the preparation of civil and criminal investigations. (Approved by the Department/Scientific Council in 1994). Line linked to the SOCIAL DENTISTRY DEPARTMENT.

FORENSIC ANTHROPOLOGY. Research in this line covers the comparative analysis of measurements of the different segments of the human body, the study of racial and ethnic characteristics, and its interest in civil and criminal forensics (Approved by the Department/Council Scientific in 1994). Line linked to the SOCIAL DENTISTRY DEPARTMENT.

DENTAL NECROPSY AND FORENSIC TANATOLOGY. The research work in this line aims to establish appropriate techniques for accessing the various topographic anatomical regions for the study and diagnosis of the etiology of death. (Approved by the Department/Scientific Council in 1990). Line linked to the SOCIAL DENTISTRY DEPARTMENT.

HEMATOLOGY ORGANIC EQUIDIUMS IN EXPERT INVESTIGATION. The work in this line of research covers the study of the components of blood and other organic liquids, such as saliva and sperm, aimed at the interests of forensic dentistry. (Approved by the Department/Scientific Council in 1993). Line linked to the SOCIAL DENTISTRY DEPARTMENT.

SEX DETERMINATION. The work in this line of research aims to determine somatic sex and genetic sex, in living or dead people, in organic tissues and organic liquids. (Approved by the Department/Scientific Council in 1992). Line linked to the SOCIAL DENTISTRY DEPARTMENT.

ESTIMATION OF HUMAN AGE. The work in this line of research covers the study of the development and growth of the various segments of the human body, establishing the age group closest to the real biological age. (Approved by the Department/Scientific Council in 1993). Line linked to the SOCIAL DENTISTRY DEPARTMENT.

HUMAN IDENTIFICATION. Idealization of human identification processes in the different characters of the teeth and the cephalic portion. (Approved by the Department/Scientific Council in 1993). Line linked to the SOCIAL DENTISTRY DEPARTMENT.

ERGONOMICS APPLIED TO DENTISTRY. Ergonomics as a science governs man's relationships with his work environment, emphasizing areas such as physics, physiology, anatomy and psychology. In this way, it provides a more harmonious working environment that facilitates greater productivity of work without compromising its quality. In dentistry, the study of ergonomics provides a better distribution of dental equipment, a better working posture and, consequently, greater productivity of the services provided. This line aims to study these relationships in the daily practice of dentistry professionals. (Approved by the Department/Scientific Council in 1994). Line linked to the SOCIAL DENTISTRY DEPARTMENT.

ASSEMBLY AND PLANNING OF DENTAL OFFICE. The assembly and planning of the dental office of the newly graduated dentistry student needs to be prepared following the principles of ergonomics, the choice of location, the distribution of professionals in the area, the job market, the type of professional practice and the population to be served. This line of research aims to study these objectives to be achieved when setting up dental offices. (Approved by the Department/Scientific Council in 1994). Line linked to the SOCIAL DENTISTRY DEPARTMENT.

INSTRUMENTATION IN DENTISTRY. INSTRUMENTATION IN DENTISTRY (Approved by the Department/Scientific Council in 1994). Line linked to the SOCIAL DENTISTRY DEPARTMENT.

WORKING TIME ANALYSIS. REDUCING WORKING TIMES IN DENTISTRY AIMS TO PROVIDE GREATER PRODUCTIVITY OF SERVICES WITH AN INCREASED DEMAND FOR PATIENTS CARE FOR. THIS LINE OF RESEARCH INTENDS TO ANALYZE WORKING TIMES IN CARE FOR PATIENTS IN DIFFERENT DENTAL SPECIALTIES, CREATING METHODS TO THE REDUCTION OF THEM. (Approved by the Department/Scientific Council in 1994). Line linked to the SOCIAL DENTISTRY DEPARTMENT.

INFORMATICS IN DENTISTRY. Informatics is the science that is currently undergoing broad development in all areas. Its use in Dentistry, with the application and creation of specific *Software*, aiming at better care and organization of services are the objectives of this line of research. (Approved by the Department/Scientific Council in 1995). Line linked to the SOCIAL DENTISTRY DEPARTMENT.

FACTORS INFLUENTIAL IN REPAIR AND ENDODONTIC TREATMENT. Study of the factors involved in post-treatment periapical repair of root canals: instrumentation and obturation techniques, intracanal medication, irrigating solutions, sealing materials. Study of the biocompatibility of materials used in e (Approved by the Department/Scientific Council in 1974). Line connected to the DEPARTMENT OF RESTORATIVE DENTISTRY.

ETIOLOGY OF DENTAL MALOCCLUSIONS AND DENTO-FACIAL ANOMALIES. Assessment of etiological factors of malocclusions, with a view to differential diagnosis aimed at planning at levels of prevention, interception and orthodontic correction (Approved by the Department/Scientific Council ficed in 1984). Line connected to the DEPARTMENT OF CHILDREN'S DENTISTRY.

PHYSICAL ANTHROPOLOGY - CEPHALOMETRY - APPLICATIONS TO ORTHODONTICS. Study of cephalic measurements with a view to evaluating craniofacial growth, its proportions within normality and its deviations within anomalies, seeking to maintain relationships with the normality of dental occlusion and/or malocclusions, and of ( Approved by the Department/Scientific Council in 1967). Line connected to the DEPARTMENT OF CHILDREN'S DENTISTRY.

DIAGNOSIS OF ORAL LESIONS. Establish among the individuals who seek the Faculty of Dentistry of Piracicaba, the most prevalent clinical findings in terms of need, in order to define the patient's profile and plan treatment. (Approved by the Department/Scientific Council in 1996). Line connected to the ORAL DIAGNOSTIC DEPARTMENT.

SIALOGRAPHY: ANATOMY AND GLANDULAR FUNCTION. Substances that are constantly used in sialography, the techniques used, radiographic images and glandular function are studied. (Approved by the Department/Scientific Council in 1995). Line connected to the ORAL DIAGNOSTIC DEPARTMENT.

THERAPY AND BIOLOGY OF THE DENTINE-PULP COMPLEX. Study, from clinical, radiological and biological points of view, the dentin-pulp complex, with a view to the application of materials and techniques in primary teeth. (Approved by the Department/Scientific Council in 1987). Line connected to the DEPARTMENT OF CHILDREN'S DENTISTRY.

KARYOLOGY. Study methods, techniques and procedures for preventing dental caries in Pediatric Dentistry, observing epidemiological data on the prevalence and incidence of dental caries in babies and children, seeking control and prevention of the disease. (Approved by the Department/Scientific Council in 1987). Line connected to the DEPARTMENT OF CHILDREN'S DENTISTRY.

DENTAL MATERIALS APPLIED TO PEDIATRIC DENTISTRY. Study dental materials from clinical, radiological and biological points of view in primary and permanent teeth, including pit and fissure sealants, dentin adhesives, composite resins and silver amalgams. (Approved by the Department/Scientific Council in 1987). Line connected to the DEPARTMENT OF CHILDREN'S DENTISTRY.

OCCLUSION IN PEDIATRIC DENTISTRY. Study the processes of development and establishment of deciduous occlusion and its relationships with the maturation of the stomatognathic system. (Approved by the Department/Scientific Council in 1988). Line connected to the DEPARTMENT OF CHILDREN'S DENTISTRY.

BIOLOGY APPLIED TO ORTHODONTICAL MECHANICS. Study of biological reactions to tooth movements caused by orthodontic mechanics. (Approved by the Department/Scientific Council in 1984). Line connected to the DEPARTMENT OF CHILDREN'S DENTISTRY.

GROWTH OF THE SKULL AND FACE. Longitudinal and cross-sectional study on human or comparative craniofacial growth, with a view to elucidating orthodontic problems. This includes studies relating to the development of the different constituent parts of the cephali set (Approved by the Department/Scientific Council in 1962). Line connected to the DEPARTMENT OF CHILDREN'S DENTISTRY.

REPAIR AND REGENERATION OF PERIODONTAL TISSUE. This line is structured to carry out clinical research aimed at studying the repair process of wounds involving periodontal tissues. The line also involves clinical and laboratory studies on guided and regeneration of tissue (Approved by the Department/Scientific Council in 1993). Line connected to the DEPARTMENT OF PROSTHESIS AND PERIODONTICS.

EXPERIMENTAL PERIODONTAL DISEASE IN ANIMALS. Study the factors involved in the development of chronic periodontal disease. (Approved by the Department/Scientific Council in 1995). Line connected to the DEPARTMENT OF PROSTHESIS AND PERIODONTICS.

EXPERIMENTAL CLINICAL PERIODONTICS. Evaluate the clinical response obtained with different forms of periodontal therapies. (Approved by the Department/Scientific Council in 1993). Line connected to the DEPARTMENT OF PROSTHESIS AND PERIODONTICS.

DENTAL MATERIALS FOR USE IN PROSTHESIS. Evaluate the physicochemical properties and dimensional stability of dental materials in prosthetics. (Approved by the Department/Scientific Council in 1993). Line connected to the DEPARTMENT OF PROSTHESIS AND PERIODONTICS.

INTERDISCIPLINARY ANALYSIS AND TREATMENT OF CRANIOMANDIBULAR DYSFUNCTIONS. Proposition, execution and evaluation of clinical treatment programs for patients with painful craniomandibular disorders, including mechanical interventions (occlusal adjustments, occlusal splints), pharmacological (anxiolytics, analgesics, muscle relaxants), psychological interventions (progressive muscle relaxation training, biofeedback, placelos ) physical and speech therapy. (Approved by the Department/Scientific Council in 1993). Line linked to the SOCIAL DENTISTRY DEPARTMENT.

ELECTROMYOGRAPHY AND CHEWING EFFICIENCY. The electromyographic evaluation of each pair of muscles involved in chewing and each mandibular movement, of patients before and after non-surgical treatment of functional changes in the stomatognathic system is a task of great clinical repercussion (Approved by the Department/Scientific Council in 1992) . Line connected to the DEPARTMENT OF PROSTHESIS AND PERIODONTICS.

HISTOPHYSIOLOGY OF THE PERIODONTAL AND DENTAL ERUPTION. The mechanism of tooth eruption, obj. of intense inv., it is not clear, although there is indication. that it is dependent on the periodontal ligament or its precursor, the dental follicle. The objective is to study: 1-through photonic and electronic microscopy (as (Approved by the Department/Scientific Council in 1988). Line linked to the DEPARTMENT OF MORPHOLOGY.

OCCLUSION IN DENTAL PROSTHESIS. Method for determining the maxillomandibular position using occlusal ferolas, Benett angle transfer techniques, incisor guide, canine guide and condylar guide for semi-adjustable articulators of the Arcon and non-Arcon type. Electromyog assessment (Approved by the Department/Scientific Council in 1993). Line connected to the DEPARTMENT OF PROSTHESIS AND PERIODONTICS.

ANALYSIS OF STRESS ON STRUCTURES USED IN ORAL REHABILITATION. Check the dissipation of applied forces through photoelasticity. (Approved by the Department/Scientific Council in 1995). Line connected to the DEPARTMENT OF PROSTHESIS AND PERIODONTICS.

PREVENTION, INTERCEPTION AND CORRECTION OF DENTAL OCCLUSION ANOMALIES. Study and development of orthodontic procedures and techniques applicable to the prevention, interception and correction of dental malocclusions, both at general dental clinic levels and at advanced levels of the orthodontic specialty (Approved by the Department/Scientific Council in 1984). Line connected to the DEPARTMENT OF CHILDREN'S DENTISTRY.

DRUG THERAPY IN PEDIATRIC DENTISTRY. Study medications from a clinical and pharmacological point of view in children (Approved by the Department/Scientific Council in 1994). Line connected to the DEPARTMENT OF CHILDREN'S DENTISTRY.

RATIONALIZATION OF DENTAL EQUIPMENT. This line of research aims to study the rationalization of dental equipment (Approved by the Department/Scientific Council in 1994). Line linked to the SOCIAL DENTISTRY DEPARTMENT.

USE OF ASSISTANT PERSONNEL IN DENTISTRY. Since 1904, the dental surgeon, with the creation of auxiliary professions in dentistry, has ceased to be the main work factor in dental care to be the center of responsibilities and delegator of functions. This line of research aims to study the work relationships between the dental surgeon and technical auxiliary staff, with an emphasis on achieving greater work productivity by improving the quality of care (Approved by the Department/Scientific Council in 1994). Line linked to the SOCIAL DENTISTRY DEPARTMENT.

PULP, PERIAPICAL AND PERIODONTAL CHANGES. Study of the development of pulpal and periapical changes. (Approved by the Department/Scientific Council in 1995). Line connected to the DEPARTMENT OF RESTORATIVE DENTISTRY.

RADIOGRAPHIC STUDY OF THE SALIVARY GLANDS. This line of research studies the anatomy and pathologies existing in the salivary glands through injection of contrast and its visualization through x-rays. (Approved by the Department/Scientific Council in 1995). Line connected to the ORAL DIAGNOSTIC DEPARTMENT.

STUDY OF THE TEMPOROMANDIBULAR JOINT. This line of research allows the development of studies on bone degeneration in the atm, disorders in the joint complex associated or not with myofacial pain syndromes. (Approved by the Department/Scientific Council in 1995). Line connected to the ORAL DIAGNOSTIC DEPARTMENT.

RADIOBIOLOGY AND RADIOPROTECTION. This line of research allows us to demonstrate studies of the biological effects caused by different types of ionizing radiation as well as these effects on different tissues. (Approved by the Department/Scientific Council in 1995). Line connected to the ORAL DIAGNOSTIC DEPARTMENT.

FILMS AND RADIOGRAPHIC PROCESSING. THIS LINE OF RESEARCH STUDY THE SENSITOMETRIC PROPERTIES OF FILM USED IN DENTAL RADIOGRAPHS AS WELL AS THE PROCESSING SOLUTIONS USED. (Approved by the Department/Scientific Council in 1995). Line connected to the ORAL DIAGNOSTIC DEPARTMENT.

IMAGENOLOGY IN DENTISTRY. Digital image evaluation. (Approved by the Department/Scientific Council in 1997). Line connected to the ORAL DIAGNOSTIC DEPARTMENT.

PREVENTION AND TREATMENT OF CERIES. ETHNICAL MATERIALS.Analysis of material and techniques aimed at preventing and treating tooth decay and its consequences for the deciduous and permanent teeth of young children. (Approved by the Department/Scientific Council in 1994). Line connected to the DEPARTMENT OF CHILDREN'S DENTISTRY.

INFLUENCE OF DRUGS ON LIVER TISSUE. As the liver tissue is the main responsible for the metabolization of drugs in the body, we aim with this line to study the possible effects and influences of medications on this tissue with laboratory work on intact livers and in regeneration, through morphological and functional analysis of the organ and clinical trials using enzyme dosages. (Approved by the Department/Scientific Council in 1992). Line linked to the DEPARTMENT OF PHYSIOLOGICAL SCIENCES.

DENTAL MATERIALS APPLIED IN DENTURES. Assessment of the cariostatic capacity of dental restorative materials; evaluation of different polymerization systems for composite resins; study of different tooth whitening agents and their influence on restorative materials. (Approved by the Department/Scientific Council in 1993). Line connected to the DEPARTMENT OF RESTORATIVE DENTISTRY.

DATA ANALYSIS METHODOLOGY IN DENTAL RESEARCH. Develops research and studies in Biostatistics, adapting new techniques and designs to dental research. (Approved by the Department/Scientific Council in 1999). Line linked to the SOCIAL DENTISTRY DEPARTMENT.

EXTRACELLULAR MATERIALS IN ORAL TISSUE. Study the expression of proteins and structure of genes related to the development and pathologies of the oral cavity. (Approved by the Department/Scientific Council in 1997). Line linked to the DEPARTMENT OF MORPHOLOGY.

EVALUATION OF MATERIALS AND SURGICAL TECHNIQUES APPLIED IN ORAL AND MAXILLO-FACIAL SURGERY. The objective of this line of research is to evaluate, in the most diverse spheres, the materials used in oral and maxillofacial surgery, testing their biocompatibility, clinical applicability and effectiveness in relation to organic tissues. (Approved by the Department/Scientific Council in 2000). Line connected to the ORAL DIAGNOSTIC DEPARTMENT.

CASE ANALYSIS IN ORAL AND MAXILLO-FACIAL SURGERY. The objective of this line of research is to verify, by critically analyzing, the casuistics and clinical results obtained in the various surgical procedures. (Approved by the Department/Scientific Council in 2000). Line connected to the ORAL DIAGNOSTIC DEPARTMENT.

TISSUE REPAIR ANALYSIS. The objective of this line of research is to verify the tissue response to therapies applicable in oral and maxillofacial surgery. (Approved by the Department/Scientific Council in 2000). Line connected to the ORAL DIAGNOSTIC DEPARTMENT.

PROGNOSTIC FACTORS OF ORAL TUMORS. This line of research aims to identify prognostic factors associated with various tumors that occur in the oral cavity. (Approved by the Department/Scientific Council in 2000). Line connected to the ORAL DIAGNOSTIC DEPARTMENT.

TMJ AND OSTEOSNTHESIS IN ULTRASTRUCTURE AND LIGHT MICROSCOPY. Comparative evaluation of the osteoinductive activities of the homologous decalcified dentin matrix and the polytetrafluoroethylene membrane in surgical bone defects in the periapical region of rabbit first mandibular molars, through hi analysis (Approved by the Department/Scientific Council in 1998). Line linked to the DEPARTMENT OF MORPHOLOGY.

ODONTOGENESIS. Evaluation of chronic ingestion of ethyl alcohol during the gestational period on ameloggenesis of lower molars in rats. Histomorphometric analysis of the enamel matrix. (Approved by the Department/Scientific Council in 1998). Line linked to the DEPARTMENT OF MORPHOLOGY.

MICROBIOLOGY APPLIED TO ENDODONTICS. Identification of microorganisms involved in pulpal and periapical pathologies. Susceptibility of microorganisms to irrigants, intracanal medications and endodontic cements. Susceptibility of microorganisms to drugs and dental materials. E (Approved by the Department/Scientific Council in 1998). Line connected to the DEPARTMENT OF RESTORATIVE DENTISTRY.

INFLAMMATION AND OROFACIAL PAIN. Study the painful and inflammatory mechanisms of the orofacial region and the pharmacokinetics, toxicity and clinical use of local anesthetics/vasoconstrictors, analgesics and anti-inflammatory drugs. (Approved by the Department/Scientific Council in 1998). Line linked to the DEPARTMENT OF CHILDREN'S DENTISTRY, DEPARTMENT OF PHYSIOLOGICAL SCIENCES.

BEHAVIOR AND STRESS. Study the physiological and behavioral changes induced by stress, pharmacokinetics, toxicity and clinical use of drugs used in its control (Approved by the Department/Scientific Council in 1998). Line linked to the DEPARTMENT OF PHYSIOLOGICAL SCIENCES, DEPARTMENT OF SOCIAL DENTISTRY.

OROFACIAL PATHOPHYSIOLOGY AND OCCLUSION. Study orofacial pathophysiology, the different aspects of occlusion and the relationships with TMJ disorders, adjacent organs and oral habits. (Approved by the Department/Scientific Council in 1998). Line linked to the DEPARTMENT OF CHILDREN'S DENTISTRY, DEPARTMENT OF PHYSIOLOGICAL SCIENCES.

PHARMACOLOGICAL STUDIES OF COMPOUNDS OF NATURAL ORIGIN AND ANTIMICROBIAL AGENTS. Chemical, pharmacological and toxicological characterization of natural products of therapeutic interest and study of the antimicrobial properties of compounds of natural and synthetic origin and their clinical use. (Approved by the Department/Scientific Council in 1998). Line linked to the DEPARTMENT OF PHYSIOLOGICAL SCIENCES.

BACTERIAL DENTAL PLAQUE. Study of the formation of cariogenic dental plaque and evaluation of the effect of anti-plaque, anti-caries and cariogenic substances. (Approved by the Department/Scientific Council in 1998). Line linked to the DEPARTMENT OF ORAL DIAGNOSIS, DEPARTMENT OF CHILDREN'S DENTISTRY, DEPARTMENT OF PHYSIOLOGICAL SCIENCES, DEPARTMENT OF SOCIAL DENTISTRY.

FLOWER STUDIES. The non-rational use of flower has motivated the investigation of its pharmacokinetics, pharmacodynamics and toxicity, with the objective of our work being to study its use in reducing the dental series, with greater efficiency and safety (Approved by the Department/Scientific Council in 1998). Line linked to the DEPARTMENT OF CHILDREN'S DENTISTRY, DEPARTMENT OF PHYSIOLOGICAL SCIENCES, DEPARTMENT OF SOCIAL DENTISTRY.

EPIDEMIOLOGY, TREATMENT AND DIAGNOSIS OF ACTION DISEASE AND RISK FACTORS. Study the occurrence of oral diseases, modulating factors and oral health promotion strategies. (Approved by the Department/Scientific Council in 1998). Line linked to the DEPARTMENT OF PROSTHESIS AND PERIODONTICS, DEPARTMENT OF PHYSIOLOGICAL SCIENCES, DEPARTMENT OF SOCIAL DENTISTRY.

GENERAL HISTOCHEMISTRY. Histochemistry of human and animal body tissues. (Approved by the Department/Scientific Council in 1996). Line linked to the DEPARTMENT OF MORPHOLOGY.

CLINICAL AND ANATOMIC INCIDENTS OF ENDODONTIC PROBLEMS. Study the internal morphology of teeth through the techniques of clearing, optical and scanning microscopy. Endodontic emergencies. (Approved by the Department/Scientific Council in 1998). Line connected to the DEPARTMENT OF RESTORATIVE DENTISTRY.

DIRECT AND INDIRECT DENTAL RESTORATIONS. Assessment of the bonding capacity of adhesive systems to enamel and dentin through mechanical tests; methods of treating dental substrate to increase adhesive capacity. (Approved by the Department/Scientific Council in 1993). Line connected to the DEPARTMENT OF RESTORATIVE DENTISTRY.

MARGINAL ADAPTATION OF DENTAL RESTORATIONS. Assessment of microleakage in direct adhesive restorations; evaluation of microleakage in indirect adhesive restorations; study of different restorative techniques using composite resin. (Approved by the Department/Scientific Council in 1993). Line connected to the DEPARTMENT OF RESTORATIVE DENTISTRY.

CLINICAL EVALUATION OF MATERIALS AND RESTORATIVE TECHNIQUES. Evaluation of different restorative materials and diagnostic methods applied in the dental clinic. (Approved by the Department/Scientific Council in 1993). Line connected to the DEPARTMENT OF RESTORATIVE DENTISTRY.

RESTORATIVE MATERIALS. The objective of this line is to study chemical reactions and properties. Handling and use techniques. Color and dimensional stability tests. Composition. Biological characteristics of restorative materials (Approved by the Department/Scientific Council in 1983). Line connected to the DEPARTMENT OF RESTORATIVE DENTISTRY.

EXPRESSION OF THE EXTRACELLULAR MATRIX IN ORAL TISSUE. Not reported (Approved by the Department/Scientific Council in 1996). Line linked to the DEPARTMENT OF MORPHOLOGY.

SEQUENTIAL IDENTIFICATION OF DNAThe work in this line of research covers the use of DNA analysis techniques (VNTR, STR, Restriction Enzymes, RFLP and Sequencing) and their applications in human identification and science. Forensic sciences and nucleic acids in neoplastic cells. (Approved by the Department/Scientific Council in 1995). Line linked to the SOCIAL DENTISTRY DEPARTMENT.

ADHERENCE IN DENTISTRY. Evaluate the adhesive capacity of restorative materials as well as techniques that can improve the adhesion of these materials to the tooth structure. (Approved by the Department/Scientific Council in 2001). Line connected to the DEPARTMENT OF RESTORATIVE DENTISTRY.

CHARACTERIZATION OF ORAL YEAST. Identification and characterization of oral yeasts and other anatomical sites. Studies with proteins, isoenzymes and DNA. (Approved by the Department/Scientific Council in 1999). Line connected to the ORAL DIAGNOSTIC DEPARTMENT.

STUDY ON THE CARIogenic ACTIVITY OF PIRACICABA AND REGION. Studies with oral streptococcus and its relationship with tooth decay. Suppression and recolonization of dental plaque. (Approved by the Department/Scientific Council in 1980). Line connected to the ORAL DIAGNOSTIC DEPARTMENT.

IDENTIFICATION AND CHARACTERIZATION OF STAPHYLOCOCUS AUREUS. Identification of Staphylococci in the clinical-dental environment. Resistance and antimicrobials and plasmid characterization. (Approved by the Department/Scientific Council in 1998). Line connected to the ORAL DIAGNOSTIC DEPARTMENT.

IDENTIFICATION BY PCR OF PERIODONTOPATHGENS OF PERIODONTAL POCKETS. Detection of periodontopathogens and periodontal pockets using the PCR technique. Correlation between the presence or absence of these microorganisms and clinical parameters. (Approved by the Department/Scientific Council in 1999). Line connected to the ORAL DIAGNOSTIC DEPARTMENT.

ORAL PATHOLOGY. Clinical, epidemiological manifestations and procedures for clinical, histopathological diagnosis and treatment of oral diseases. Development of experimental models of Oral Pathology. (Approved by the Department/Scientific Council in 1999). Line connected to the ORAL DIAGNOSTIC DEPARTMENT.

PERIODONTAL PATHOLOGY. Clinical, histological and molecular evaluation of gingival enlargement induced by drugs such as cyclosporine, nifedipine and hereditary gingival enlargement. (Approved by the Department/Scientific Council in 1999). Line connected to the ORAL DIAGNOSTIC DEPARTMENT.

SALIVARY GLAND PATHOLOGIES. Clinical, epidemiological, microscopic and immunohistochemical aspects of oral cavity salivary gland tumors and their prognostic factors. (Approved by the Department/Scientific Council in 1999). Line connected to the ORAL DIAGNOSTIC DEPARTMENT.

ORAL YEASTS. Assessment of diseases caused by oral yeasts, as well as isolation, counting, identification and correlation with local and systemic predisposing factors for these diseases. (Approved by the Department/Scientific Council in 1999). Line connected to the ORAL DIAGNOSTIC DEPARTMENT.

TECHNIQUES FOR ORAL REHABILITATION. Study of the different techniques used for oral rehabilitation of different dental prostheses. (Approved by the Department/Scientific Council in 1999). Line connected to the DEPARTMENT OF PROSTHESIS AND PERIODONTICS.

CELL BIOLOGY AND BIOMATERIALS. Evaluate "in vitro" the histophysiology of cellular elements of human periodontal structures and
evaluate "in vitro" and "in vivo" the biomaterials used in Periodontics. (Approved by the Department/Scientific Council in 2001). Line connected to the ORAL DIAGNOSTIC DEPARTMENT.

100

SPINOCELLULAR CARCINOMA. Assessment of the clinical, microscopic, immunohistochemical and molecular aspects of squamous cell carcinomas and their variants in the head and neck region. (Approved by the Department/Scientific Council in 1991). Line connected to the ORAL DIAGNOSTIC DEPARTMENT.

101

BONE METABOLISM. Interference of inflammatory mediators in bone metabolism. (Approved by the Department/Scientific Council in 2001). Line linked to the DEPARTMENT OF MORPHOLOGY, DEPARTMENT OF PROSTHESIS AND PERIODONTICS.

102

ABRASION AND POLISHING. The finishing and polishing of restorative dental materials are important steps in obtaining clinically successful restorations. Polishing and cleaning are procedures that can lead to the surface of the enamel or restorative material... (Approved by the Department/Scientific Council in 1991). Line connected to the DEPARTMENT OF RESTORATIVE DENTISTRY.

103

CRANIOMANDIBULAR DISORDERS. Study of craniomandibular disorders and their therapies. The projects are also related to the face and its aesthetic, phonetic and TMJ consequences. (Approved by the Department/Scientific Council in 1999). Line connected to the DEPARTMENT OF PROSTHESIS AND PERIODONTICS.

104

IMPLANTODONTICS AND OSSEOINTEGRATION. Its objective is the clinical and laboratory study of the phenomena involved in the healing and repair processes of the bone *interface* of titanium implants, as well as peri-implant defects. (Approved by the Department/Scientific Council in 1993). Line connected to the DEPARTMENT OF PROSTHESIS AND PERIODONTICS.

105

EXTRACELLULAR MATRIX II. Biochemical and molecular evaluation of extracellular matrix glycoproteins in normal oral tissues and in pathological processes (Approved by the Department/Scientific Council in 1999). Line connected to the ORAL DIAGNOSTIC DEPARTMENT.

106

CARIOLOGY APPLIED TO RESTORATIVE DENTISTRY. Verify the in vitro presence of incipient lesions, cavities, discolorations or other changes involving enamel or dentin, proposing a differential diagnosis or improving diagnostic methods (Approved by the Department/Scientific Council in 2004). Line connected to the DEPARTMENT OF RESTORATIVE DENTISTRY.

107

REGENERATIVE PROCESSES. Study of bone tissue regeneration in animals. (Approved by the Department/Scientific Council in 2005). Line linked to the DEPARTMENT OF MORPHOLOGY.

108

KINESIOLICAL AND MORPHOFUNCTIONAL BEHAVIOR OF THE MUSCLE AND SKELETAL SYSTEMS. Assessment of the morphofunctional behavior of the muscular and skeletal systems in joint, muscular and skeletal changes through radiographs, electromyography and morphometry. (Approved by the Department/Scientific Council in 2004). Line linked to the DEPARTMENT OF MORPHOLOGY.

109

CELL BIOLOGY IN PERIODONTICS. Study of cellular and molecular phenomena involved in periodontal regeneration and the pathogenesis of periodontal disease (Approved by the Department/Scientific Council in 2005). Line connected to the DEPARTMENT OF PROSTHESIS AND PERIODONTICS.

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